Signaling in Inflammation Lab

  

RESEARCH GROUP’S MISSION

 

The main objective of our group is to study the intracellular signaling pathways and molecules involved on the resolution of inflammation. More specifically, we have been working with different proteins, such glucocorticoid-induced proteins (AnxA1, GILZ and MKP-1) and heme oxigenase-1, and their potential as pro-resolving molecules on acute inflammatory process. We have been also studing the resolution of inflammatory response during a bacterial infection model, specifically Streptococcus pneumoniae lung infection. Additionally, we have been exploring the role of the Plasminogen/Plasmin system to leukocyte migration and resolution of inflammation. On the context of human inflammatory disease, our group is interested in the signaling pathways involved on production of pro- inflammatory cytokines (MAPK, PI3K/Akt, NF-kB) as well as on the resolution pathways (AnxA1 and GILZ) by using peripheral blood mononuclear cells.

 

 

TEAM

 

 

Coordinator

 

           

  Dr. Lirlândia Pires de Sousa

 

She is currently an adjunct professor in the Department of Clinical and Toxicological Analysis, Facultyof Pharmacy,UFMG, Associate Researcher at the Laboratory of Immunopharmacology of ICB/UFMG and guiding along the Graduate Program in Cell Biology from the ICB,UFMG.

 

 

 

 

PHD Students          

 

 

  Juliana Priscila Vago da Silva

 

  Kátia Maciel Lima   

 

 

  

Master Students       

 

 

  Aline Alves Fortunato do Carmo  

 

  Luiza Oliveira Perucci  

 

  Mayara Chaves Faria  

 

  Nathália Teixeira Pietrani  

  

 

 

Undergratuate Students

 

 

   Luciana Pádua Tavares